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Neuroendocrinology

Kiss1 expressed in the amygdala in rodents

Nature Reviews Endocrinology volume 7, page 313 (2011)Cite this article

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Kiss1 is expressed outside the hypothalamus in the amygdala in rodents, a recent study reveals.

Kisspeptin—a neuropeptide encoded by the Kiss1 gene—is a major regulator of puberty and fertility. Kiss1 expression in the brain has been found in two discrete areas of the hypothalamus and each hypothalamic population has different functions in the regulation of reproduction. However, “by chance, during one of our previous studies in rodents, we noticed a third novel population of Kiss1-expressing neurons in the amygdala region,” says senior researcher Alexander Kauffman of the University of California San Diego.

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ORIGINAL RESEARCH PAPER

  1. Kim, J. et al. Regulation of Kiss1 expression by sex steroids in the amygdala of the rat and mouse. Endocrinology doi:10.1210/en.2010-1498

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Authors
  1. Carol Wilson
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Wilson, C. Kiss1 expressed in the amygdala in rodents. Nat Rev Endocrinol 7, 313 (2011). https://doi.org/10.1038/nrendo.2011.63

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