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Therapy

Neuroendocrine cancer—are two radionuclides better than one?

A Correction to this article was published on 17 August 2012

This article has been updated

Peptide-receptor radionuclide therapy with radiolabelled somatostatin analogues is a successful new treatment modality for patients with neuroendocrine tumours. Usually, 90yttrium (90Y)-coupled or 177lutetium (177Lu)-coupled somatostatin analogues are used, but a new study claims that combining the two radiopharmaceuticals results in improved overall survival.

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Change history

  • 10 July 2012

    In the version of this article initially published online and in print there was a mistake in the use of 177Lu-DOTATATE instead of 177Lu-DOTATOC in the first sentence of the third paragraph. The correct sentence should have read "Villard et al.1 compared the efficacy of PRRT with 90Y-DOTATOC to that of PRRT with combined 90Y-DOTATOC and 177Lu-DOTATOC in a large series of patients with metastatic neuroendocrine cancer." The error has been corrected for the HTML and PDF versions of the article.

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The author declares an association with the following company: Advanced Accelerator Applications (stock holder/director).

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Kwekkeboom, D. Neuroendocrine cancer—are two radionuclides better than one?. Nat Rev Endocrinol 8, 326–328 (2012). https://doi.org/10.1038/nrendo.2012.64

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