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Metabolism

Bacterial–host interplay in circadian regulation of metabolism

Nature Reviews Endocrinology volume 11, page 2 (2015)Cite this article

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Disrupted circadian rhythms in mice and humans lead to changes in the composition and function of the microbiota that in turn affect the host metabolism, reveal Eran Elinav and colleagues in Cell.

The increased prevalence of metabolic diseases in Western countries is associated with lifestyle changes, such as “the tendency to disrupt normal circadian sleep–wake patterns, for instance by frequent flying to different time zones or performing shift work,” comments Elinav.

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References

  1. Thaiss, C. A. et al. Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis. Cell 10.1016/j.cell.2014.09.048

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  1. Joana Osório
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Osório, J. Bacterial–host interplay in circadian regulation of metabolism. Nat Rev Endocrinol 11, 2 (2015). https://doi.org/10.1038/nrendo.2014.194

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