Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlight
  • Published:

Gut microbiota

Antidiabetic drug treatment confounds gut dysbiosis associated with type 2 diabetes mellitus

Nature Reviews Endocrinology volume 12, page 61 (2016)Cite this article

Subjects

Access through your institution
Buy or subscribe

Patients with type 2 diabetes mellitus (T2DM) have been reported to have alterations in the composition and function of their gut microbiota, which is suggestive of a microbe-mediated mechanism of disease. However, few studies reporting this correlation have taken into account the antidiabetic medications used by patients, which could themselves affect the gut microbiota.

intrinsic gut microbiota imbalances associated with a given disorder might be masked or confounded by patients' treatment regimens

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Forslund, K. et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature http://dx.doi.org/10.1038/nature15766

Download references

Authors
  1. David Holmes
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Holmes, D. Antidiabetic drug treatment confounds gut dysbiosis associated with type 2 diabetes mellitus. Nat Rev Endocrinol 12, 61 (2016). https://doi.org/10.1038/nrendo.2015.222

Download citation

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/nrendo.2015.222

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing