Table 3 Target panel versions based on ClinVar gold star variant evidence level

From: Consensus Statement on next-generation-sequencing-based diagnostic testing of hereditary phaeochromocytomas and paragangliomas

Panel type

Gene list

Sample type*

Basic

Evidence level 3 and 4 for germ line mutations

Blood

Extended

Evidence level 2 for germ line mutations (rare)

Blood

Comprehensive

All somatic mutations and all levels of evidence

Blood and tumour

  1. *Buccal cells can be used as a source of germ line DNA when blood is not available.
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