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Epigenetics

A silent inheritance

Nature Reviews Genetics volume 10, page 283 (2009)Cite this article

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Chromatin templates that are bound by the PRC1 core complex (PCC) prior to DNA replication are completely replicated in vitro. Notably, the known inhibitory effect of PCC on chromatin remodelling persists through chromatin replication. So, PCC binds to, and affects, chromatin through DNA replication in vitro.

Polycomb repressor complex 1 (PRC1) proteins remain bound to chromatin during DNA replication...

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References

ORIGINAL RESEARCH PAPER

  1. Francis, N. J. et al. Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro. Cell 137, 1–13 (2009)

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FURTHER READING

  1. Probst, A. V. et al. Epigenetic inheritance during the cell cycle. Nature Rev. Mol. Cell Biol. 10, 192–206 (2009)

    Article  CAS  Google Scholar 

  2. Schwartz, Y. B. & Pirrotta, V. Polycomb silencing mechanisms and the management of genomic programmes. Nat. Rev. Genet. 8, 9–22 (2007)

    Article  CAS  Google Scholar 

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  1. Associate Editor Nature Reviews Molecular Cell Biology,

    Francesca Cesari

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  1. Francesca Cesari
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Cesari, F. A silent inheritance. Nat Rev Genet 10, 283 (2009). https://doi.org/10.1038/nrg2585

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  • DOI: https://doi.org/10.1038/nrg2585

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