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Motor neuron disease

Anatomical spread of amyotrophic lateral sclerosis predicts survival

Nature Reviews Neurology volume 7, page 598 (2011)Cite this article

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Amyotrophic lateral sclerosis frequently manifests in a single region of the body, followed by spread to other regions. Research from Japan has now shown that rapid recruitment of a second body region to the disease process is predictive of poor survival. The authors propose that this knowledge could assist in the planning of disease-management strategies, and in the counseling of patients and their families.

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ORIGINAL RESEARCH PAPER

  1. Fujimura-Kiyono, C. et al. Onset and spreading patterns of lower motor neuron involvements predict survival in sporadic amyotrophic lateral sclerosis. J. Neurol. Neurosurg. Psychiatry 82, 1244–1249 (2011)

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Anatomical spread of amyotrophic lateral sclerosis predicts survival. Nat Rev Neurol 7, 598 (2011). https://doi.org/10.1038/nrneurol.2011.160

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