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Stroke

Novel oral anticoagulants for stroke prevention are associated with reduced risk of intracranial haemorrhage

Nature Reviews Neurology volume 9, page 659 (2013)Cite this article

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New-generation oral anticoagulants carry a lower risk of intracranial haemorrhage (ICH) than does warfarin, a new systematic review and meta-analysis shows. Chatterjee et al. analysed six studies, which had recruited a total of 57,491 patients with atrial fibrillation who received anticoagulants for stroke prevention. All novel anticoagulants, which interact directly with coagulating proteins, were associated with a 50% reduced risk of ICH compared with warfarin-based vitamin K antagonists.

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ORIGINAL RESEARCH PAPER

  1. Chatterjee, S. et al. New oral anticoagulants and the risk of intracranial hemorrhage. JAMA Neurol. doi:10.1001/jamaneurol.2013.4021

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Novel oral anticoagulants for stroke prevention are associated with reduced risk of intracranial haemorrhage. Nat Rev Neurol 9, 659 (2013). https://doi.org/10.1038/nrneurol.2013.239

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