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Dementia

Visual hallucinations in neurodegenerative disease are associated with volume loss in the right anterior insula

Nature Reviews Neurology volume 11, page 4 (2015)Cite this article

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Visual hallucinations are common in patients with dementia with Lewy bodies (DLB), and can also be present in Alzheimer disease (AD). Voxel-based morphometry in 78 patients with AD, half of whom experienced hallucinations, detected specific regions of grey and white matter atrophy associated with hallucinations; the right anterior insula was of core importance. Autopsy of four patients who had experienced hallucinations revealed combined AD and DLB pathology.

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References

  1. Blanc, F. et al. Right anterior insula: core region of hallucinations in cognitive neurodegenerative diseases. PLoS ONE 9, e114774 (2014)

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Visual hallucinations in neurodegenerative disease are associated with volume loss in the right anterior insula. Nat Rev Neurol 11, 4 (2015). https://doi.org/10.1038/nrneurol.2014.249

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