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Epilepsy

Noninvasive detection of deep brain seizures

Nature Reviews Neurology volume 12, page 493 (2016)Cite this article

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Seizures in deep cortical regions have been detected with noninvasive recordings for the first time in a recently published study. A computational approach enabled detection of mesial temporal lobe seizures that conventional EEG did not pick up, opening the door to further understanding the role of these seizures in epilepsy and other neurological disorders.

Nonconvulsive seizures in deep brain regions such as the mesial temporal lobes are known to occur in patients with epilepsy, and some evidence suggests that they also occur in Alzheimer disease (AD). Many of these seizures are undetectable because they produce no conventional EEG signal; consequently, they are known as 'scalp-negative seizures'.

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References

  1. Lam, A. D. et al. Widespread changes in network activity allow non-invasive detection of mesial temporal lobe seizures. Brain http://dx.doi.org/10.1093/brain/aww198 (2016)

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Authors
  1. Ian Fyfe
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Fyfe, I. Noninvasive detection of deep brain seizures. Nat Rev Neurol 12, 493 (2016). https://doi.org/10.1038/nrneurol.2016.121

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  • DOI: https://doi.org/10.1038/nrneurol.2016.121

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