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Stroke

CT identifies patients in stroke treatment window

Nature Reviews Neurology volume 13, page 5 (2017)Cite this article

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Multimodal CT that measures water uptake in stroke lesions can indicate the time of stroke onset, according to recent research. The approach could determine whether patients with unknown time of stroke onset are eligible to receive thrombolysis.

In new work, André Kemmling and colleagues have developed a technique to predict whether patients with unknown time of onset are within the required 4.5 h window. They used two types of CT to measure water uptake in the infarct over time. “We combined the high sensitivity of perfusion CT to precisely target the core lesion, with the high specificity of density change in native CT to designate infarct-related water uptake,” explains Kemmling.

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References

  1. Minnerup, J. et al. Computed tomography based quantification of lesion water uptake identifies patients within 4.5 hours of stroke onset: a multicenter observational study. Ann. Neurol. http://dx.doi.org/10.1002/ana.24818 (2016)

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  1. Ian Fyfe
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Fyfe, I. CT identifies patients in stroke treatment window. Nat Rev Neurol 13, 5 (2017). https://doi.org/10.1038/nrneurol.2016.184

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  • DOI: https://doi.org/10.1038/nrneurol.2016.184

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