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Multiple sclerosis

10-year study shines a light on grey matter atrophy in MS

Nature Reviews Neurology volume 14, page 3 (2018)Cite this article

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“SBM is a data-driven technique that relies on the use of independent component analysis — a multivariate method that identifies common spatial patterns in the data,” explains lead author Niels Bergsland. “We undertook the current project in an attempt to better characterize the specific spatial characteristics of grey matter atrophy in patients with MS.”

Bergsland and colleagues analysed brain MRI scans taken in 152 patients with relapsing–remitting MS, at baseline and after 10 years. The participants were divided into two groups according to the presence or absence of confirmed disability progression (CDP) at the end of the study (n = 85 and n = 67, respectively).

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References

  1. Bergsland, B. et al. Gray matter atrophy patterns in multiple sclerosis: a 10-year source-based morphometry study. Neuroimage Clin. 17, 444–451 (2017)

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  1. Heather Wood
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Wood, H. 10-year study shines a light on grey matter atrophy in MS. Nat Rev Neurol 14, 3 (2018). https://doi.org/10.1038/nrneurol.2017.167

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