Therapeutic strategies are in development that aim to use TREG cells in autoimmune diseases. The feasibility of such an approach is challenged, however, by recent findings suggesting that the chronic phase of autoimmune inflammation might not be controlled by these cells. What impact could this study have on the development of TREG cell-based therapies for human diseases?
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Schulze-Koops, H., Skapenko, A. TREG cell control of autoimmune inflammation: a matter of timing?. Nat Rev Rheumatol 6, 620–621 (2010). https://doi.org/10.1038/nrrheum.2010.155
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DOI: https://doi.org/10.1038/nrrheum.2010.155
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