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Paediatric rheumatic disease

Defining clinically inactive disease in juvenile dermatomyositis

Nature Reviews Rheumatology volume 8, pages 638–639 (2012)Cite this article

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Achievement of a state of inactive disease has become a realistic goal in juvenile dermatomyositis. The development of a standardized definition of inactive disease in this disorder is a critical step in measuring outcomes, and might now be a step closer.

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References

  1. Ruperto, N. et al. Criteria to define response to therapy in paediatric rheumatic diseases. Eur. J. Clin. Pharmacol. 67 (Suppl 1.), 125–131 (2011).

    Article  Google Scholar 

  2. Lazarevic, D. et al. The PRINTO criteria for clinically inactive disease in juvenile dermatomyositis. Ann. Rheum. Dis. http://dx.doi.org/10.1136/annrheumdis-2012-201483.

  3. Mendez, E. P. et al. US incidence of juvenile dermatomyositis, 1995–1998: results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Registry. Arthritis Rheum. 49, 300–305 (2003).

    Article  Google Scholar 

  4. Ruperto, N. et al. The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis. Arthritis Care Res. (Hoboken) 62, 1533–1541 (2010).

    Article  Google Scholar 

  5. Singh, J. A. et al. Development of classification and response criteria for rheumatic diseases. Arthritis Rheum. 55, 348–352 (2006).

    Article  Google Scholar 

  6. Johnson, S. R. et al. Classification criteria in rheumatic diseases: a review of methodologic properties. Arthritis Rheum. 57, 1119–1133 (2007).

    Article  Google Scholar 

  7. Schmeling, H. et al. Nailfold capillary density is importantly associated over time with muscle and skin disease activity in juvenile dermatomyositis. Rheumatology (Oxford) 50, 885–893 (2011).

    Article  Google Scholar 

  8. Baechler, E. C. et al. An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. Mol. Med. 13, 59–68 (2007).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, ON, Canada

    Nadia J. Luca & Brian M. Feldman

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  1. Nadia J. Luca
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  2. Brian M. Feldman
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Correspondence to Brian M. Feldman.

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The authors declare no competing financial interests.

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Luca, N., Feldman, B. Defining clinically inactive disease in juvenile dermatomyositis. Nat Rev Rheumatol 8, 638–639 (2012). https://doi.org/10.1038/nrrheum.2012.165

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