Non-radiographic axial spondyloarthritis (nr-axSpA) and radiographic axial spondyloarthritis (r-axSpA) are considered to be different spectra of the same disease. Accumulating data suggest a low transition rate from nr-axSpA to r-axSpA in patients with early disease and identify inflammation, smoking and HLA-B27 positivity as factors associated with transition.
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Acknowledgements
Pedro M. Machado acknowledges funding from the National Institute for Health Research (NIHR) Rare Diseases Translational Research Collaboration (RD TRC) and from the NIHR University College London Hospitals (UCLH) Biomedical Research Centre. The views expressed in this article are those of the author and not necessarily those of the UK National Health Service (NHS), the NIHR or the Department of Health.
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Navarro-Compán, V., Machado, P. Sacroiliac joint radiographic progression — speed and determinants. Nat Rev Rheumatol 12, 380–382 (2016). https://doi.org/10.1038/nrrheum.2016.86
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DOI: https://doi.org/10.1038/nrrheum.2016.86
