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Osteoporosis

Romosozumab to rebuild the foundations of bone strength

Biologic agents targeting key proteins involved in bone homeostasis are revolutionizing the management of osteoporosis. New clinical data support the use of these novel therapies to rapidly increase bone mass and decrease the risk of fractures.

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Figure 1: Differential effects of bone-forming agents on bone surfaces.

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Correspondence to Serge L. Ferrari.

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The author declares that he has received research funding and consultancy fees from Amgen, MSD and UCB.

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Ferrari, S. Romosozumab to rebuild the foundations of bone strength. Nat Rev Rheumatol 14, 128 (2018). https://doi.org/10.1038/nrrheum.2018.5

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