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Tattle tales

Recent NMR structures of bovine immunodeficiency viral TAR RNA–Tat peptide complexes have revealed a new β-hairpin RNA recognition motif. These complexes exhibit intriguing new variations on the recurring themes in nucleic acid recognition.

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References

  1. Kashanchi, F. et al. Nature 367, 295–299 (1994).

    Article  CAS  Google Scholar 

  2. Cullen, B.R. Cell 73, 417–420 (1993).

    Article  CAS  Google Scholar 

  3. Greenblatt, J., Nodwell, J.R. & Mason, S.W. Nature 364, 401–406 (1993).

    Article  CAS  Google Scholar 

  4. Zhou, Q. & Sharp, P.A. EMBO J. 14, 321–328 (1995).

    Article  CAS  Google Scholar 

  5. Draper, D.E. A. Rev. Biochem. 593, 593–620 (1995).

    Article  Google Scholar 

  6. RNA-Protein Interactions (eds. Nagai, K. & Mattaj, I.W: IRL Press, New York, 1994).

  7. Chen, L. & Frankel, A.D. Biochemistry 33, 2708–2715 (1994).

    Article  CAS  Google Scholar 

  8. Chen, L. & Frankel, A.D. Proc. natn. Acad. Sci. U.S.A. 92, 5077–5081 (1995).

    Article  CAS  Google Scholar 

  9. Puglisi, J.D., Chen, L, Blanchard, S. & Frankel, A.D. Science 270, 1200–1203 (1995).

    Article  CAS  Google Scholar 

  10. Ye, X., Kumar, R.A. & Patel, D.J. Chemistry &Biology 2, 827–840 (1995).

    CAS  Google Scholar 

  11. Puglisi, J.D., Tan, R., Calnan, B.J., Frankel, A.D. & Williamson, J.R. Science 257, 76–80 (1992).

    Article  CAS  Google Scholar 

  12. Churcher, M.J. et al. J. molec. Biol. 230, 90–110 (1993).

    Article  CAS  Google Scholar 

  13. Willbold, D., Rosin-Arbesfeld, R., Sticht, H., Frank, R. & Rösch, P. Science 264, 1584–1587 (1994).

    Article  CAS  Google Scholar 

  14. Derse, D. & Newbold, S.H. Virology 194, 530–536 (1994).

    Article  Google Scholar 

  15. Weeks, K.M. & Crothers, D.M. Science 261, 1574–1577 (1993).

    Article  CAS  Google Scholar 

  16. Seeman, N.C., Rosenberg, J.M. & Rich, A. Proc. natl. Acad. Sci. U.S.A. 73, 804–809 (1976).

    Article  CAS  Google Scholar 

  17. Pavletich, N.P. & Pabo, C.O. Science 252, 809–817 (1991).

    Article  CAS  Google Scholar 

  18. Burd, C.G. & Dreyfuss, G. Science 265, 615–621 (1994).

    Article  CAS  Google Scholar 

  19. Lazinski, D., Gradzielska, E., Das, A. Cell 59, 207–218 (1989).

    Article  CAS  Google Scholar 

  20. Tan, R., Chen, L., Buettner, J.A., Hudson, D. & Frankel, A.D. Cell 73, 1031–1040 (1993).

    Article  CAS  Google Scholar 

  21. Weeks, K.M. & Crothers, D.M. Cell 66, 577–588 (1991).

    Article  CAS  Google Scholar 

  22. Tao, J. & Frankel, A.D. Proc. natn. Acad. Sci. U.S.A. 89, 2723–2726 (1992).

    Article  CAS  Google Scholar 

  23. Aboul-ela, F., Karn, J. & Varani, G. J. molec. Biol. 253, 313–332 (1995).

    Article  CAS  Google Scholar 

  24. Puglisi, J.D., Chen, L., Frankel, A.D. & Williamson, J.R. Proc. natl. Acad. Sci. U.S.A. 90, 3680–3684 (1993).

    Article  CAS  Google Scholar 

  25. Dieckmann, T. & Feigon, J. Curr. Opin. struct. Biol. 4, 745–749 (1994).

    Article  CAS  Google Scholar 

  26. Nikonowicz, E.P. & Pardi, A. J. mol. Biol. 232, 1141–1156 (1993).

    Article  CAS  Google Scholar 

  27. Nikonowicz, E.P., et al. Nucleic Acids Res. 20, 4507–4513 (1992).

    Article  CAS  Google Scholar 

  28. Batey, R.T., Inada, M., Kujawinski, E., Puglisi, J.D. & Williamson, J.R. Nucleic Acids Res. 20, 4515–4523 (1992).

    Article  CAS  Google Scholar 

  29. Carvalho, M. & Derse, D. J. Virol. 65, 3468–3474 (1991).

    Article  CAS  Google Scholar 

  30. Bayer, P., et al. J. molec. Biol. 247, 529–535 (1995).

    CAS  PubMed  Google Scholar 

  31. Berkhout, B. Nucleic Acids Res. 20, 27–31 (1991).

    Article  Google Scholar 

  32. Hoffman, D.W., Colvin, R.A., Garcia-Blanco, M.A. & White, S.W. Biochemistry 32, 1096–1104 (1993).

    Article  CAS  Google Scholar 

  33. Carroll, R., Martarano, L. & Derse, D. J. Virol. 65, 3460–3467 (1991).

    Article  CAS  Google Scholar 

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Sundquist, W. Tattle tales. Nat Struct Mol Biol 3, 8–11 (1996). https://doi.org/10.1038/nsb0196-8

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