The NMR structure of a copper-binding domain of the protein responsible for Menkes' syndrome demonstrates that the Cys-xx-Cys motif is used by prokaryotes and eukaryotes to deal with heavy metals.
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References
Tu¨mer, Z. & Horn, N. Ann. Med. 28, 121–129 (1996).
Vulpe, C., Levinson, B., Whitney, S., Packman, S. & Gitschier, J. Nature Genet. 3, 7–13 (1993).
Bull, P.C., Tomas, G.R., Rommens, J.M., Forbes, J.R. & Cox, D.W. Nature Genet. 5, 327–337 (1993).
Solioz, M. & Vulpe, C. Trends Biochem. Sci. 21, 237–241 (1996).
Gitschier, J. et al. Nature Struct. Biol. 5, 47–54 (1997).
Solioz, M. & Odermatt, A. J. Biol. Chem., 270, 9217–9221 (1994).
Steele, R.A. & Opella, J. Biochemistry 36, 6885–6895 (1997).
Foster, T.J. CRC Crit. Rev. Microbiol. 15, 117–140 (1987).
Lutsenko, S., Petrukhin, K., Cooper, M.J., Gilliam, C.T. & Kaplan, J.H. J. Biol. Chem. 272, 18939–18944 (1997).
Adman, E., Watenpaugh, K.D. & Jensen, L.H. Proc. Natl. Acad. Sci., USA 72, 4854–4858 (1975).
Robbins, et al. J. Mol. Biol. 221, 1269–1293 (1991).
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McRee, D. Living with metal ions. Nat Struct Mol Biol 5, 8–10 (1998). https://doi.org/10.1038/nsb0198-8
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DOI: https://doi.org/10.1038/nsb0198-8
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