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StARTing to understand cholesterol transfer

Nature Structural Biology volume 7, pages 445–447 (2000)Cite this article

The crystal structure of a lipid transfer START domain has been solved and shown to contain a hydrophobic tunnel that likely binds cholesterol. These results have implications for understanding the mechanism of action of the steroidogenic acute regulatory protein (StAR), which is indispensable in steroid biosynthesis.

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  1. the Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, 79430, Texas, USA

    Douglas M. Stocco

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  1. Douglas M. Stocco
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Stocco, D. StARTing to understand cholesterol transfer. Nat Struct Mol Biol 7, 445–447 (2000). https://doi.org/10.1038/75834

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