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Ion tamers

Nature Structural Biology volume 5, pages 409–411 (1998)Cite this article

The structure of calsequestrin, the major calcium-binding protein of skeletal muscle sarcoplasmic reticulum, consists of three thioredoxin folds that condense to form an acidic platform for calcium adsorption.

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References

  1. Williams, R.J.P. & Wacker, W.E.C. J. Am. Med Assoc. 201, 96–105 (1967).

    Article  CAS  Google Scholar 

  2. Kretsinger, R.H., In Calcium-binding proteins and calcium function (eds Wasserman. R. H. et al.) 63–72 (North Holland Press, New York; 1977).

    Google Scholar 

  3. MacLennan, D.H., Rice, W.J. & Green, N.M. J. Biol. Chem. 272, 28815–28818 (1997).

    Article  CAS  Google Scholar 

  4. Ringer, S.A. J. Physiol. 4, 29–42 (1883).

    Article  CAS  Google Scholar 

  5. Herzberg, O. & James, N.M.G. Nature 313, 653–659 (1985).

    Article  CAS  Google Scholar 

  6. Gagné, S.M., Tsuda, S., Li, M.X., Smillie, L.B. & Sykes, B.D. Nature Struct. Biol. 2, 784–789 (1995).

    Article  Google Scholar 

  7. MacLennan, D.H. & Wong, P.T.S. Proc. Natl. Acad. Scl. USA 468, 1231–1235 (1971).

    Article  Google Scholar 

  8. Guo, W. & Campbell, K.P. J. Biol. Chem. 270, 9027–9030 (1995).

    Article  CAS  Google Scholar 

  9. Zhang, L., Kelley, J., Schmeisser, G., Kobayashi, Y.M. & Jones, L.R. J. Biol. Chem. 272, 23389–23397 (1997).

    Article  CAS  Google Scholar 

  10. Rail, J.A. News Physiol. Sci. 11, 249–255 (1996).

    Google Scholar 

  11. Wang, S. et al. Nature Struct. Biol. 5, 476–483 (1998).

    Article  CAS  Google Scholar 

  12. Holmgren, A. J. Biol. Chem. 264, 13963–13966 (1989).

    CAS  PubMed  Google Scholar 

  13. Holmgren, A., Söderberg, B.-O., Eklund, H & Brändén, C.-I Proc. Natl. Acad. Sci. USA 72, 2305–2309 (1975).

    Article  CAS  Google Scholar 

  14. Fliegel, L. et al. Proc. Natl. Acad, Sci. USA 84, 1167–1171 (1987).

    Article  CAS  Google Scholar 

  15. Scott, B.T., Simmerman, H.K.B., Collins, J.H., Nadal-Ginard, B. & Jones, L.R. J. Biol. Chem. 263, 8958–8964 (1988).

    CAS  PubMed  Google Scholar 

  16. Nagar, B., Overduin, M., Ikura, M. & Rini, J.M. Nature 380, 360–364 (1996)

    Article  CAS  Google Scholar 

  17. Freedman, R.B., Hirst, T.R. & Tuite, M.F. Trends Biochem. Sci. 19, 331–336 (1994).

    Article  CAS  Google Scholar 

  18. Kemmick, J., Darby, N.J., Dijkstra, K., Nigles, M. & Creighton, I.E. Curr. Biol. 7, 239–245 (1997).

    Article  Google Scholar 

  19. Darby, N.J., Kemmick, J. & Creighton, I.E. Biochemistry 35, 10517–10528 (1996).

    Article  CAS  Google Scholar 

  20. Mazzarella, R.A., Srinivasan, M., Haugejorden, S.M. & Green, M. J. Biol. Chem. 265, 1094–1101 (1990).

    CAS  Google Scholar 

  21. Van, P.N., Rupp, K., Lampen, A. & Söling, H.-D. Eur. J. Biochem. 213, 789–795 (1993).

    Article  CAS  Google Scholar 

  22. Lucero, H.A., Lebeche, D. & Kaminer, B. J. Biol. Chem. 273, 9857–9863 (1998).

    Article  CAS  Google Scholar 

  23. Leberer, E., Charuk, J.H.M., Green, N.M. & MacLennan, D.H. Proc. Natl. Acad. Sci. USA 86, 6047–6051 (1989).

    Article  CAS  Google Scholar 

  24. Krause, K.-H., Milos, M., Luan-Rilliet, Y., Lew, D.P. & Cox, J.A. J. Biol. Chem. 266, 9453–9459 (1991).

    CAS  PubMed  Google Scholar 

  25. Tanaka, M., Ozawa, T., Maurer, A.M., Cortese, J. & Fleischer, S. Arch. Biochem. Biophys. 251, 369–378 (1986).

    Article  CAS  Google Scholar 

  26. Williams, R.W. & Beeler, T.J. J. Biol. Chem. 261, 12408–12413 (1986).

    CAS  PubMed  Google Scholar 

  27. Shannon, T.R. & Bers, D.M. Biophys. J. 73, 1524–1531 (1997).

    Article  CAS  Google Scholar 

  28. Somlyo, A.V., Gonzalez-Serratos, H., Shuman, H., McClennan, G. & Somlyo, A.P. J. Cell Biol. 90, 577–594 (1981).

    Article  CAS  Google Scholar 

  29. Franzini-Armstrong, C., Kenney, L.J. & Varriano-Marston, E. J. Cell Biol. 105, 49–56 (1987).

    Article  CAS  Google Scholar 

  30. Saito, A., Seller, S., Chu, A. & Fleischer, S. J. Cell Biol. 99, 875–885 (1984).

    Article  CAS  Google Scholar 

  31. Maurer, A., Tanaka, M., Ozawa, T. & Fleischer, S. Proc. Natl. Acad. Sci. USA 82, 4036–4040 (1985).

    Article  CAS  Google Scholar 

  32. Williams, R.J.P. Biochim. Biophys. Acta 505, 1–44 (1978).

    Article  CAS  Google Scholar 

  33. Clairmont, C.A., De Maio, A. & Hirschberg, C.B. J. Biol. Chem. 267, 3983–3990 (1992).

    CAS  PubMed  Google Scholar 

  34. Williams, D.B. Biochem. Cell Biol. 73, 123–132 (1995).

    Article  CAS  Google Scholar 

  35. Krause, K.H. & Michalak, M. Cell 88, 439–443 (1997).

    Article  CAS  Google Scholar 

  36. Wada, I. et al. J. Biol. Chem. 266, 19599–19610 (1991).

    CAS  PubMed  Google Scholar 

  37. Nigam, S.K. et al. J. Biol. Chem. 269, 18744–18749 (1994).

    Google Scholar 

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Authors and Affiliations

  1. Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, M5G 116, Canada

    David H. MacLennan

  2. MRC Group in Membrane Biology, Department of Medicine, University of Toronto, Toronto, Ontario, M5S 1A8, Canada

    Reinhart A. F. Reithmeier

Authors
  1. David H. MacLennan
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  2. Reinhart A. F. Reithmeier
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Correspondence to David H. MacLennan.

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MacLennan, D., Reithmeier, R. Ion tamers. Nat Struct Mol Biol 5, 409–411 (1998). https://doi.org/10.1038/nsb0698-409

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