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Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin

Nature Structural Biology volume 4, pages 779–783 (1997)Cite this article

Amaranthus caudatus agglutinin contains a novel arrangement of four β-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when ‘masked’ by other sugars.

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Author information

Author notes

  1. Thomas R. Transue

    Present address: Department of Ultrastructure, Free University of Brussels, B-1640, Sint-Genesius-Rode, Belgium

  2. Hanqing Mo

    Present address: Department of Biochemistry, Shanghai Medical University, Shanghai, China

Authors and Affiliations

  1. Biophysics Research Division, The University of Michigan, Ann Arbor, Michigan, 48109-1055, U.S.A.

    Thomas R. Transue, Alexander K. Smith & Mark A. Saper

  2. Department of Biological Chemistry, The University of Michigan, Ann Arbor, Michigan, 48109-1055, U.S.A.

    Thomas R. Transue, Hanqing Mo, Irwin J. Goldstein & Mark A. Saper

Authors
  1. Thomas R. Transue
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  2. Alexander K. Smith
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  3. Hanqing Mo
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  4. Irwin J. Goldstein
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  5. Mark A. Saper
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Transue, T., Smith, A., Mo, H. et al. Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin. Nat Struct Mol Biol 4, 779–783 (1997). https://doi.org/10.1038/nsb1097-779

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