Supplementary Figure 5: Structure-based sequence alignment of the CNOT2 and CNOT3.
From: Structure and assembly of the NOT module of the human CCR4–NOT complex
Secondary structure elements as determined from the CNOT2 and CNOT3 structure are shown above the alignment. Symbols are as described in Supplementary Fig. 2. Residues interacting with the respective partner proteins are indicated by dots above the alignments and are colored blue for CNOT1, purple for CNOT2 and green for CNOT3. Residues forming the lock are marked with black diamonds, and residues at the junction between the symmetric and asymmetric lobes of the ternary complex are marked with pink triangles. The species abbreviations are the same as those in Supplementary Fig. 2.
