Supplementary Figure 5: Enrichment levels of overlapping remodeler and DHS sites. | Nature Structural & Molecular Biology

Supplementary Figure 5: Enrichment levels of overlapping remodeler and DHS sites.

From: Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions

Supplementary Figure 5

(a) Additional example of genome browser view displaying Brg1, Chd4, and Snf2h ChIP-seq occupancy and DNase I hypersensitivity patterns at a region on chromosome 6. (b-d) Box plots of tag density enrichment (log2 scale) of the indicated remodeler binding sites overlapping DNase I hypersensitive sites (DHS) and remodeler binding sites not associated with DHS sites. (e) Box plot of tag density enrichment (log2 scale) of DHS sites overlapping remodeler binding sites (Remodeler) and DHS sites not associated with remodeler binding. The number of each site type is indicated below the corresponding box plot. (f) Aggregate plot of the average tag density of DHS sites (hotspot) at regions occupied by: all remodelers (any/all combinations of remodeler binding, black), no remodelers (red), Brg1 only (light blue), Chd4 only (brown), or Snf2h only (pink).

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