Supplementary Figure 7: Remodeler binding at affected DHS sites.
From: Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions
(a-c) Genome browser views of ChIP-seq remodeler binding at DNase I hypersensitive (DHS, DNaseI-seq) sites affected by dominant-negative remodeler expression. In each image tag densities are displayed relative to the indicated genomic coordinates. The left image is an example of an affected site bound only by the wild-type version of the mutant remodeler. The right image displays binding by all three remodelers at the affected DHS site. Changes in hypersensitivity in the absence (+Tet) or presence (-Tet) of the indicated dominant-negative remodeler are overlayed and highlighted by arrows. (d-f) Overlay of remodeler binding at DHS sites in the presence or absence of the indicated dominant-negative remodeler protein. Displayed are scatter plots of DHS site tag density in the presence of each dominant-negative protein (y-axis) compared to DHS site tag density in the absence of this protein. Inset, original scatter plots of DNase I hypersensitivity from Fig. 5.
