Supplementary Figure 7: CSR-1 regulates transcription independently of MES-4.
From: Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape
(a) ChIP-qPCR results with L4-staged worms showing the enrichment of MES-4 at CSR-1 target regions compared to the non-target regions. There are no differences in MES-4 binding in drh-3(ne4253) mutant compared to WT. The enrichment has been calculated relative to the non-target gene ZK381.2. Error bars indicate the range (n = 2 biological replicates). (b) ChIP-qPCR results with L4-staged worms, as in (a), showing the levels of H3K36me3 normalized to the total levels of histone H3 at CSR-1 target regions compared to the non-target regions. There are no differences in the levels of H3K36me3 in drh-3(ne4253) mutant compared to WT. Error bars indicate the range (n = 2 biological replicates).
