Supplementary Figure 3: Secondary structure of the TYK2 FERM-SH2 domain, and comparison of TYK2 primary sequence to the other human JAK family members
From: Structural basis of recognition of interferon-α receptor by tyrosine kinase 2
Secondary structure elements are labeled using conventions established for the FAK FERM domain and SH2 domain of Lck. Secondary structural elements are displayed above the alignments, with helices displayed as cylinders, strands displayed as block arrows, and loops displayed as lines. Secondary structure is labeled and domain structure colors matched between the structure and the alignment. Residues contacting IFNAR1 are shaded in yellow.
