Supplementary Figure 6: Interaction sites in the Pan2–Pan3 complex. | Nature Structural & Molecular Biology

Supplementary Figure 6: Interaction sites in the Pan2–Pan3 complex.

From: The structure of the Pan2–Pan3 core complex reveals cross-talk between deadenylase and pseudokinase

Supplementary Figure 6

Structure of the yeast Pan2ΔN–Pan3ΔN complex with the bound AMP molecule at the deadenylase active site. Also shown are the nucleotides (ATPγS) and the region corresponding to the Tryptophan-binding pocket from the structures of Pan3 orthologues28, after optimal superposition. Abbreviations: PK (pseudokinase), nt (nucleotide), UCH (ubiquitin C-terminal hydrolase)

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