Supplementary Figure 4: Suppressors and enhancers of expanded-CUG toxicity have distinct effects on expanded-CUG nuclear-foci accumulation. | Nature Structural & Molecular Biology

Supplementary Figure 4: Suppressors and enhancers of expanded-CUG toxicity have distinct effects on expanded-CUG nuclear-foci accumulation.

From: Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans

Supplementary Figure 4

Confocal SM-FISH images of GFP RNA transcripts (white), DAPI stained nucleus (blue) and merge of C. elegans muscle cells. The strains imaged were 123CUG and the control 0CUG, in different RNAi gene inactivations: empty vector control (ctrl), C06A1.6, str-67, mrt-2, npp-4 and smg-2. Yellow arrows indicate expanded CUG nuclear foci.

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