Supplementary Figure 7: Concentration-response curves showing responses of bombesin receptors to the cognate ligand bombesin and saquinavir. | Nature Structural & Molecular Biology

Supplementary Figure 7: Concentration-response curves showing responses of bombesin receptors to the cognate ligand bombesin and saquinavir.

From: PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Supplementary Figure 7

(a) BB1 receptor, Tango assay. (b) BB2 receptor, Tango assay. (c) BB1 receptor, calcium mobilization assay. (d) BB2 receptor, calcium mobilization assay. (e) BB3 receptor, PI hydrolysis assay. Data are expressed as mean ± SEM of triplicate determinations, and curves were fitted using Graphpad Prism.

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