Supplementary Figure 8: Concentration-dependent agonist activity of various compounds at MRGPRX2 receptors in the Tango assay compared with the activity of the known ligand SB 205607.
From: PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
(a) and (c) Tango arrestin recruitment assays, (b) PI hydrolysis. Data are expressed as mean ± SEM of triplicate determinations, and curves were fitted using Graphpad Prism.
