Supplementary Figure 3: Sequence alignment of human ST8SiaIII with human ST8SiaII and ST8SiaIV.
From: Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation
Motifs highlighted (polybasic region, blue; large, green; polysialyltransferase domain, cyan; small, orange; III, black; very small, violet) and predicted transmembrane helix shown in grey. The header shows the most prevalent residues in small letters and conserved residues in capitalized red letters. Black asterisks refer to glycosylation sites Asn93, 113, 160 and 206 of ST8SiaIII. The alignment was created with Clustal Omega (http://www.ebi.ac.uk/Tools/msa/clustalo/) and UCSF Chimera68.
