Supplementary Figure 4: Base composition of the U-rich motif in HeLa and SH-SY5Y cells.
From: Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt
Heatmaps illustrate the positional frequency of each of the 64 possible trimers within Unkempt binding sites between 15 nts upstream and downstream of the binding site maxima in HeLa (a) and SH-SY5Y cells (b). Traces of individual trimers are displayed in the same order as in Fig. 3a. Plots above each heatmap profile the mean enrichment of different clusters of triplets color-coded as shown in the heatmap (UAG in red, the 13 enriched U-rich triplets in blue, and all other triplets in gray). The scale below the heatmap indicates fold enrichment over the median triplet frequency in a 103-nt window around the binding site maxima.
