Supplementary Figure 1: Properties of single-chain variants. | Nature Structural & Molecular Biology

Supplementary Figure 1: Properties of single-chain variants.

From: Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

Supplementary Figure 1

(a) Size-exclusion chromatography profiles of single-chain variants from design cycle 1 assessed using a Superose 6 Increase 5/150GL (24 ml column volume) gel filtration column. (b) Dynamic light scattering analysis of sc9 DS-Cav1. (c) Engineered single-chain RSV F glycoproteins with interprotomer disulfides shown with the SDS-PAGE shown in uncropped format.

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