Supplementary Figure 3: Structural details of single-chain variants.
From: Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV
(a) Structural alignment of PR-DM and SC-TM RSV F vaccine candidates with sc9-10 A149 Y458C variant. (b) Design cycle 4 comprising combinations of interprotomer disulfides (DS2) and other mutations highlighted here in orange and detailed in Table S1.
