Supplementary Figure 4: Chemical-shift-perturbation plots of the Hsp90 N-domain mutants.
From: Importance of cycle timing for the function of the molecular chaperone Hsp90
Chemical shift perturbation of the 1H,15N-HSQC spectra from Supplementary Figure 3 between the indicated mutant and the wildtype of the N-terminal domain of yeast Hsp90. Negative chemical shifts indicate shifting residues that could not be assigned in the complex. Residues which are not assigned in the wildtype are indicated by gaps. Chemical shift changes larger than 0.15 ppm are indicated on top of the bars. The red lines indicate the cut-off values used in Figure 2.
