Supplementary Figure 8: Possible interactions between S domain and GspS.
From: Structural insights into the secretin translocation channel in the type II secretion system

(a) Hydrophobic interactions between α12 (cyan) and α11 (pink) of Vc_GspD (electrostatic surface on background). (b) Possible interactions between GspS and GspD S domain. PA3611 (PDB code 3NPD), a homolog of GspS, exhibits a hydrophobic crevice on the surface (left panel). In the presence of GspS, α12 will bind to the hydrophobic crevice (right panel), helping GspD position onto the outer membrane.