Supplementary Figure 3: Association of inverted repeats and operons with C. elegans replication origins.
From: The gastrula transition reorganizes replication-origin selection in Caenorhabditis elegans
(a) Boxplots showing the percentage of association of inverted repeats (IRs) with pre-gastrula and post-gastrula-specific origins (top graphs) and the reverse correlation (bottom panels), compared with random expectation, in chromosome arms and center (left and right panels respectively). *, P<10-15 (according to the distribution function of the normal distribution); n.s., non-significant difference with random. (b) Boxplots showing the number of pre-gastrula (green) and post-gastrula-specific (orange) origin summits in operons, compared with random data. *, P<10-20 (according to the distribution function of the normal distribution). Data are shown as mean ± s.d. (c) Distribution (%) of pre-gastrula (green) and post-gastrula-specific (orange) replication origins around operon transcription start sites (TSS) (mean percentage ± standard error) in chromosome arms and center.
