Supplementary Figure 7: Residual plot for multivariate analysis to determine effects of nuclear localization on mutation frequencies.
From: Nuclear topology modulates the mutational landscapes of cancer genomes
A) Residual plot of multiple linear regression ‘Mutation rates ~ LAD + replication timing + GC% + gene density + H3K9me3 + phastCons’. Red lines: smoothers between residuals and fitted values from linear model. B) Residual plot of random forest regression ‘Mutation rates ~ LAD + replication timing + GC% + gene density + H3K9me3 + phastCons’. Red lines: smoothers between residuals and fitted values from the nonparametric random forest regression.
