Supplementary Figure 5: Surface representation of the ternary complex structure. PglB- acceptor peptide-LLO complex.

(a) Surface representation of the ternary complex structure of PglB bound to acceptor peptide and synthetic, inhibitory LLO analog. PglB is colored grey, N-EL5 in turquoise, C-EL5 in purple, bound peptide in orange, bound LLO in yellow. (b) Close-up view of a. The acceptor peptide and inhibitory LLO are shown in orange and yellow sticks, respectively. The substrates are bound to cavities at opposite entrances / exits of the PglB tunnel.