Supplementary Figure 4: Cap exchange is not prevented in WT spermatocytes expressing TERB1 mutants that disrupt the TRF1-TERB1 interface.
From: Dissecting the telomere–inner nuclear membrane interface formed in meiosis
(a) Schematic depiction of TRF1 and TERB1 signal width and localization in early and late pachytene. While the TERB1 signal does not undergo a significant change in width throughout pachytene, the TRF1 signal becomes more diffuse resulting in an increase in its outer diameter. (b) WT late pachytene spermatocytes expressing GFP-TERB1 L647E, GFP-TERB1 T648D, GFP-TERB1 P649E, or GFP-TERB1 R651E-R652E (green) stained with TRF1 (red) and SYCP3 (blue) antibodies.
