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GTPase twins in the SRP family

Two recent structural studies on the GTPases of the bacterial signal recognition particle–receptor complex reveal how direct interactions between the two ribonucleotides in a shared GTP-binding cavity contribute to the assembly and the GTPase-activated disassembly of this targeting complex.

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Mandon, E., Gilmore, R. GTPase twins in the SRP family. Nat Struct Mol Biol 11, 115–116 (2004). https://doi.org/10.1038/nsmb0204-115

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