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The how and Y of cold shock

A combined structural and biochemical analysis of an essential stress protein in Escherichia coli provides the first detailed insights into a bacterial translation mechanism designed to cope with cold shock conditions.

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Figure 1: The binding site of protein Y on the ribosome overlaps with A- and P-site tRNA.
Figure 2: Scheme for protein Y–mediated regulation under cold-shock conditions.

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Wilson, D., Nierhaus, K. The how and Y of cold shock. Nat Struct Mol Biol 11, 1026–1028 (2004). https://doi.org/10.1038/nsmb1104-1026

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