Figure 4 | Nutrition & Diabetes

Figure 4

From: Insulin detemir attenuates food intake, body weight gain and fat mass gain in diet-induced obese Sprague–Dawley rats

Figure 4

Effects of Det and Glar on RNA levels of white adipose tissue markers of lipogenesis. RNA isolated from epididymal fat of rats of all treatment groups (Veh, Det and Glar) after 4 weeks of diet consisting of either LFD (n=5 per group) or HFD (n=6–8 per group) was assessed by real-time PCR for changes in RNA levels of WAT lipogenic markers, fatty acid synthase (FAS) (a) and lipoprotein lipase (LPL) (b). RNAs of interest were normalized to RPL13α and for comparative analysis, RNA ratios were normalized to the Veh LF control. Data are presented as the mean±s.e.m. and were analyzed by two-way ANOVA. For all panels, analysis with Bonferroni's post-test shows: *P<0.05 and ***P<0.001 for Veh vs Det; #P<0.05, βP<0.001 for Glar vs Det comparisons.

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