Table 2 Study outcomes: psoriasis and obesity

From: The association between psoriasis and obesity: a systematic review and meta-analysis of observational studies

Study

Study period

Outcome ascertainment

Obesity in control patients (BMI in kg m−2)

Obesity in psoriasis patients (BMI in kg m−2)

Measure of association (95% CI)

aNaldi et al.17

1988–1997

Interview/clinical examination

BMI30: n=57 (8.3%)

BMI30: n=71 (12.9%)

BMI30:

AOR 1.9 (1.2–2.8)

aHerron et al.14

Not reported

Questionnaire

Mean BMI of 26.2 (s.d. 5.1)

Median BMI of 25.7

Mean BMI of 29.1 (s.d. 7.3)

Median BMI of 27.8

OR 2.39 (1.98–2.90)

aNeimann et al.18

1987–2002

OXMIS/Read

BMI>30:

Mild Ps: n=36 117 (13.1%)

Severe Ps: n=1 093 (13.0%)

BMI>30:

Mild Ps: n=13 404 (15.8%)

Severe Ps: n=545 (20.7%)

BMI>30:

Mild Ps: OR 1.29 (1.26–1.32)

Mild Ps: AOR 1.27 (1.24–1.31)

Severe Ps: OR 1.84 (1.60–2.11)

Severe Ps: AOR 1.79 (1.55–2.05)

Cohen et al.11

Not reported

Diagnosis in database

Obesity: n=1 561 (23.5%)

Obesity: n=100 (29.4%)

OR 1.4 (1.1–1.7)

AOR 1.3 (1.0–1.7)

aKaye et al.15

1991–2005

OXMIS/Read

BMI30: n=11 996 (5.5%)

BMI30: n=2 760 (6.3%)

BMI30:

HR 1.18 (1.14–1.23)

Cohen et al.12

Not reported

Diagnosis of obesity in database

Obesity: n=1 768 (3.6%)

Obesity: n=1 419 (8.4%)

OR 2.4 (2.3–2.6)

AOR 1.7 (1.5–1.9)

Xiao et al.23

1999–2007

Medical code consistent with obesity

Obesity: n=183 (12.03)

Obesity: Mild Ps: n=227 (14.02%)

Severe Ps: n=296 (20.10%)

Mild Ps: OR 1.41 (1.08–1.85)

Mild Ps: AOR 1.42 (1.06–1.91)

Severe Ps: OR 1.51 (1.15–1.98)

Severe Ps: AOR 1.52 (1.13–2.04)

aDriessen et al.13

Not reported

Manual chart review; BMI30

Mean BMI of 24.9 (s.d. not reported)

Mean BMI of 28.5 (s.d. not reported)

BMI30:

OR 5.49 (3.09–9.74)

Takahashi et al.21

2006–2008

Manual chart review

Obesity: n=36 (22.7%)

Obesity: n=60 (39.7%)

OR 2.24 (1.36–3.69)

aSchmitt et al.19

2003–2004

ICD-10

Obesity: n=329 (10.5%)

Obesity: n=490 (15.6%)

OR 1.58 (1.36–1.83)

AOR 1.63 (1.39–1.90)

aAugustin et al.10

2005

ICD-10

Obesity: n=136 118 (10.4%)

Obesity: n=6 055 (17.8%)

PR 1.72 (1.68–1.76)

aAl-Mutairi et al.9

2003–2007

Manual chart review

BMI>30: n=195 (17%)

BMI>30:

Mild Ps: n=372 (32.5%)

Severe Ps: n=49 (41%)

BMI>30:

Mild Ps: OR 2.36 (1.93–2.87)

Severe Ps: OR 3.42 (2.30–5.10)

aWarnecke et al.22

2009–2010

Questionnaire/clinical assessment

BMI>30: n=33 (33%)

Mean BMI of 27.7 (s.d. 5.6)

BMI>30: n=44 (44%)

Mean BMI of 30.1 (s.d. 7.7)

AOR 1.03 (0.97–1.09)

aZhang et al.24

1997–2009

Clinical assessment

BMI30: n=30 (2.6%);

Mean BMI of 22.86 (s.d. 3.37)

BMI30: n=179 (4.0%);

Mean BMI of 23.29 (s.d. 3.25)

BMI30: OR 1.68 (1.13–2.49)

aShapiro et al.20

1993–2006

ICD-9

Obesity: n=94 (8.7%)

Obesity: n=143 (13.3%)

OR 1.60 (1.22–2.11)

AOR 1.32 (0.99–1.76)

Langan et al.16

Not reported

Read codes (THIN database)

BMI 30–35: n=7 678 (20.5%)

BMI>35: n=4 907 (13.1%)

BMI 30–35: n=887 (23.5%)

BMI>35: n=662 (17.5%)

BMI>30: OR 1.38 (1.29–1.48)

AOR 1.25 (1.16–1.34)

  1. Abbreviations: AOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; HR, hazard ratio; ICD, International Classification of Disease; OXMIS, Read, Oxford Medical Information System and Read diagnostic codes; PR: prevalence ratio; THIN, The Health Improvement Network database.
  2. aDenotes that obesity was the primary study outcome.