Figure 1 | Nutrition & Diabetes

Figure 1

From: Beyond the fourth wave of genome-wide obesity association studies

Figure 1

Development during the obesity GWAS waves. The progression of the four obesity GWAS waves (2007–2010); genome-wide significant associated loci associating with BMI, waist circumference and WHR, respectively, identified in individual GWAS (black), in both individual GWAS and meta-analysis (green) and in meta-analyses alone (blue). The number of identified genome-wide significant loci increases concurrently with an increase in individuals included in the studies (grey bars), having a decreasing effect size as a consequence (squares). Effect sizes are taken from Tables 1, 2, 3.

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