Figure 1
From: Beyond the fourth wave of genome-wide obesity association studies

Development during the obesity GWAS waves. The progression of the four obesity GWAS waves (2007–2010); genome-wide significant associated loci associating with BMI, waist circumference and WHR, respectively, identified in individual GWAS (black), in both individual GWAS and meta-analysis (green) and in meta-analyses alone (blue). The number of identified genome-wide significant loci increases concurrently with an increase in individuals included in the studies (grey bars), having a decreasing effect size as a consequence (squares). Effect sizes are taken from Tables 1, 2, 3.