Table 2 Association of genetic risk scores with log-transformed cardiometabolic trait levels in 1649 women

From: Genetic risk score and adiposity interact to influence triglyceride levels in a cohort of Filipino women

Genetic risk score

β

95% CI

P-value

R2

R2 (genetic risk score alone)a

CRP genetic risk score

0.19

0.15

0.23

4.81E−20

0.22

0.04

HDL-C genetic risk score

−0.04

−0.05

−0.04

1.81E−29

0.14

0.07

TG genetic risk score

0.07

0.06

0.08

3.38E−28

0.18

0.06

  1. Abbreviations: CI, confidence interval; CRP, C-reactive protein; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride.
  2. Association results from model 2; covariates were age, principal components, postmenopausal status, overweight/obese status, elevated waist circumference, % energy intake from saturated fat, energy intake, environmental hygiene, illness and socioeconomic status (outcome was the related log-transformed trait).
  3. Proportion of variance explained by the genetic risk score alone (see Subjects and Methods).
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