Table 1 Characteristics and eating behavior scores at baseline and 6 months in intervention and control participants

From: Pilot randomized trial demonstrating reversal of obesity-related abnormalities in reward system responsivity to food cues with a behavioral intervention

 

Control

Intervention

P-values

 

N

Mean (s.e.m.)

N

Mean (s.e.m.)

 

Baseline

 Sex (% female)

5

4 (80)

8

4 (50)

0.56

 Age

5

53.40 (5.10)

8

47.38 (3.93)

0.37

 Height (m)

5

1.65 (0.03)

8

1.70 (0.04)

0.40

 Weight (kg)

5

82.94 (4.88)

8

83.18 (2.77)

0.96

 Body mass index

5

30.42 (1.75)

8

28.87 (0.82)

0.38

 Craving inventory—trait score

4

138.00 (17.93)

5

88.20 (23.35)

0.15

 Hunger score

4

8.25 (1.65)

6

2.67 (0.76)

0.01

 Disinhibition score

4

12.50 (0.96)

6

6.33 (2.14)

0.05

 Restraint score

4

6.58 (2.06)

6

6.67 (1.41)

0.97

6 Months

 Weight (kg)

5

85.07 (5.59)

8

76.89 (3.17)

0.19

 Body mass index

5

31.21 (2.07)

8

26.71 (1.09)

0.06

 Craving inventory—trait score

4

151.58 (13.70)

5

67.63 (12.96)

<0.01

 Hunger score

4

10.25 (1.11)

6

2.96 (1.66)

0.01

 Disinhibition score

4

13.97 (0.71)

6

5.15 (1.33)

0.001

 Restraint score

4

5.83 (2.10)

6

15.06 (0.65)

0.001

Change (6 months minus baseline)

 Weight (kg)

5

2.14 (1.14)

8

−6.30 (1.04)

<0.001

 Body mass index

5

0.79 (0.44)

8

−2.16 (0.32)

<0.001

 Craving inventory—trait score

4

13.58 (22.11)

6

−20.57 (11.33)

0.19

 Hunger score

4

2.00 (0.71)

7

0.29 (1.42)

0.39

 Disinhibition score

4

1.47 (0.67)

7

−1.18 (1.96)

0.32

 Restraint score

4

−0.75 (2.02)

7

8.39 (1.21)

<0.01

  1. Subjects in this functional magnetic resonance imaging (fMRI) study were drawn from a larger randomized trial of the intervention versus a wait-listed control group. Not all participants in the fMRI studies completed the questionnaires and numbers shown here are for completers at both time points. In the larger population, changes in all variables noted here were significant.8, 9, 10 Differences between groups in changes over time in weight and body mass index were analyzed in the log 10 scale to approximate the normal distribution. Craving trait and dietary restraint, hunger and disinhibition were measured assessed as described in Subjects and Methods section.