Table 1 Liver fat and body composition before and after 7 weeks of PUFA or SFA overeating

From: NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass

 

PUFA (n=15) baseline

Mean absolute change

SFA (n=20) baseline

Mean absolute change

P value (t-test)

Body weight, kg

67.4±2.2

1.2±0.3

64.9±1.59

1.5±0.3

0.560

BMI, kg m−2

21.7±0.6

0.40±0.09

19.9±0.3

0.45±0.07

0.702

Liver fat, % (MRI)

0.91 ±0.1

0.03±0.08

1.17±0.2

0.5±0.08

0.077

Lean tissue, L (MRI)

42.5±2.4

0.80±0.2

42.0±1.5

0.32±0.2

0.044

VAT, L (MRI)

1.20±0.2

0.090±0.06

0.80±0.09

0.21±0.04

0.073

Total body fat, L (MRI)

17.5±1.8

0.72±1.2

13.6±1.1

1.43±0.85

0.046

  1. Abbreviations: BMI, body mass index; MRI, magnetic resonance imaging; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid; VAT, visceral adipose tissue. The presented data are means±the standard error of the mean. P-values are generated from unpaired two sided t-tests. Thirty-five individuals were included compared with 37 in the original study.6 The PUFA group included 10 males and 5 females while the the SFA group included 14 males and 6 females.