Figure 4
Effect of EPA supplementation on adiposity and steatosis in InsrP1195L/+/HFD mice at 18–20 weeks of age. (a) Computed tomographic images at the level of lower end of right kidney. Visceral and subcutaneous fat are indicated in pink and yellow, respectively. (b) Weight of epididymal WAT. (c) Immunostaining of caveolin in epididymal fat. (d) Mean adipocyte size. Scale bar: 200 μm. (e) Histogram of the cell area of four mouse groups. (f) HE staining of the liver. (g) TG content in the liver. (b, d, e, g) Data are mean±s.e.m. *P<0.05, **P<0.01, ***P<0.001. The number in the bottom of the columns (b, d, g) and in the parenthesis (e) denotes sample size.
