Table 1 Patients and cell characteristics

From: Overexpression of matrix metalloproteinase 1 in dermal fibroblasts from DNA repair-deficient/cancer-prone xeroderma pigmentosum group C patients

Fibroblasts

Age at biopsy

Race

Phenotype

Clinical characteristics

Onset of tumors

FMD

16 years

Caucasian

NA

NA

NA

FH29

30 years

Caucasian

NA

NA

NA

FH84

28 years

Black

NA

NA

NA

XP148

12 years

Caucasian

XP-C

Multiple BCCs and SCCs, face and exposed areas

9 years

XP188VI

7 years

Caucasian

XP-C

Several SCC and 1 BCC on the face

ND

XP373VI

4 years

Caucasian

XP-C

1 facial BCC

2 years

XP424VI

17 years

Caucasian

XP-C

3 facial BCC, several pigmented lesions (ephelides, naevus)

17 years

XP433VI

2 months

Caucasian

XP-C

NA

NA

XP521VI

29 years

Black

XP-C

Photophoby. SCC of the lip. Multiple lentigines. Small eye carcinomas

14 years

  1. Abbreviations: BCC, basal cell carcinomas; NA, not applicable; ND, not determined; SCC, squamous cell carcinomas; XP, xeroderma pigmentosum group C.